I had the same issue. The first Lectora 17 course that I published, none of the buttons worked, activities didn’t work, etc. My LMS Administrator had to change a setting in order for it to work….guessing it was the setting that you mentioned in your message.
She is used to it now….think I might be one of the few Developees in my company using Lectora 17 for course development. So you are not alone!
Ps…..I published to both versions of SCORM…it didn’t matter. She had to make the adjustment on the LMS side.